Yan Mei Wang

Titles

Assistant Professor

Office Contact Information

Office

213 Crow

Mailbox

Physics Department, CB 1105
Washington University
One Brookings Drive
St. Louis, MO 63130-4899, USA

Phone

(314) 935-7478

Fax

(314) 935-6219

Email contact form

URL

Research Group Website

Research Interests

Our group is a single molecule biophysics lab. We are affiliated with the Department of Physics and the Division of Biology and Biomedical Sciences at Washington University in St. Louis. Our research interests focus on elucidating biological mechanisms at the molecular level using single molecule fluorescence imaging techniques. Current biological mechanisms of interest are gene expression and control mechanisms, where the kinetics and pathways of single gene regulator proteins and their interactions with DNA are investigated in vitro and in vivo, cell division control protein dynamics, flagella transport protein dynamics, and photo-characterization of photosynthesis proteins - phycobilisomes. To extract quantitative information from the frequently convoluted images of the molecules, we explore and develop novel analytical methods.

We are seeking motivated graduate students and postdocs to join the group. Participations of undergraduate students are welcome.

Selected Publications

M. DeSantis, S. DeCenzo, J-L. Li, and Y.M. Wang, "Precision analysis for standard deviation measurements of single immobile fluorescent molecule images," Optics Express, 18, 6563-6576, (2010)
Selected by the editor-in-chief, Gregory Faris, for publication in the most recent issue of the Virtual Journal for Biomedical Optics (VJBO). Detailed version, arXiv:0908.0015.

S. DeCenzo, M. DeSantis, and Y.M. Wang, "Single-image separation measurements of two unresolved fluorophores," Optics Express, 18, 16628-16639, (2010)

Y. M. Wang, E. C. Cox and R. Austin, "Single molecule measurements of repressor protein 1D diffusion on DNA," Phys. Rev. Lett., 97, 048302, (2006).

Y. M. Wang, J. Tegenfeldt, W. Reisner, R. Riehn, Xiao-Juan Guan, Ling Guo, Ido Golding, E. C. Cox, J. Sturm and R. Austin, "Single-molecule studies of repressor-DNA interactions show long-range interactions," Proc. Natl. Acad. Sci. USA, 102, 9796-9801, (2005).

Yan Mei Wang's Complete Publications List

Education

2002 Ph. D., University of California, Berkeley, Physics

1996 B.A., University of California, Los Angeles, Physics

Professional History

2006- Assistant Professor, Washington University

2005, fall Lecturer, Physics Department, Princeton University

2002-2006 Postdoctoral researcher, Physics Department, Princeton University